Evaluation of Exalenz Bioscience's BreathID for Helicobacter pylori detection. (March 2015)

• Record Type: Journal Article
• Authors: Broide, Efrat; Shirin, Haim
• Is Part Of: Expert review of molecular diagnostics. Volume 15:Number 3(2015)
• Page Start: 299
• Page End: 312
• Publication Date: 2015-03
• Subjects: Molecular diagnosis -- Periodicals; 616.0758205
• DOI: 10.1586/14737159.2015.982537
• Languages: English
• ISSNs: 1473-7159

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Carbon-labeled urea breath tests, which have high sensitivity and specificity, are the preferred method used in epidemiological studies, screening dyspeptic patients and assessing eradication or recurrence of <italic>Helicobacter pylori</italic> infection. The principle of the ¹³C-urea breath test relies upon the ability of the <italic>H. pylori</italic> urease to hydrolyze the orally administered ¹³C-urea. The BreathID^® (Exalenz Bioscience Inc., Union, NJ, USA) provides a competitive solution for breath testing, including unique features such as automatic continuous breath collection and analysis. This is an unattended convenient test, with no human error as the correct part of the breath is collected and patients' assistance is not required. The test results are available in real time at the point of care and enable shortened breath testing procedures. Additionally, several studies showing expanded utility of the BreathID in pediatrics, after therapy and during proton pump inhibitors intake, further support the safety and performance of the BreathID in the diagnosis of <italic>H. pylori.</italic></p> </abstract>