KSHV‐TK is a tyrosine kinase that disrupts focal adhesions and induces Rho‐mediated cell contraction. (3rd December 2014) - Gill, Michael B
Abstract Gammaherpesviruses are known to encode very inefficient thymidine kinases. KSHV thymidine kinase is actually a tyrosine kinase that induces focal adhesion disassembly via its interaction with known regulators including members of the Crk‐related family of adaptor proteins.