Effectiveness of a heparinoid‐containing moisturiser to treat senile xerosis. (10th October 2014)

• Record Type: Journal Article
• Authors: Hayama, Koremasa; Takano, Yusaku; Tamura, Jin; Tagami, Hachiro; Terui, Tadashi
• Is Part Of: Australasian journal of dermatology. Volume 56:Number 1(2015:Feb.)
• Page Start: 36
• Page End: 39
• Publication Date: 2014-10-10
• Subjects: Dermatology -- Periodicals; Dermatology -- Australasia -- Periodicals; 616.5005
• DOI: 10.1111/ajd.12179
• Languages: English
• ISSNs: 0004-8380

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="ajd12179-sec-0001" sec-type="section"> <title>Background and Objectives</title> <p>With the increasing elderly population in Japan, skin problems have become a greater concern. A heparinoid‐containing moisturiser is frequently used in Japan, but there is a lack of evidence for its efficacy in treating senile xerosis. To determine whether there is a correlation between age and the hydration state of the stratum corneum (SC) assessed by skin capacitance, and to evaluate the efficiency of a heparinoid‐containing moisturiser and a bed bath to treat senile xerosis.</p> </sec> <sec id="ajd12179-sec-0002" sec-type="section"> <title>Methods</title> <p>We recruited 73 individuals to assess the hydration state of the SC on their flexor forearm by measuring their skin capacitance. To evaluate the efficacy of a heparinoid‐containing moisturiser on senile xerosis, we recruited seven inpatients with an inactive daily life (IDL) who had senile xerosis. They were treated with the moisturiser in addition to a bed bath in two different protocols, and we measured the skin capacitance on their flexor forearms on days 0, 7 and 14.</p> </sec> <sec id="ajd12179-sec-0003" sec-type="section"> <title>Results</title> <p>There was a weak negative correlation (−0.3854, <italic>P</italic> < 0.01) between skin capacitance and age. Following the moisturiser treatments, the seven inpatients had increased hydration of both arms on days 7 and 14. The skin capacitance of the right forearm slightly decreased on day 14, even though it was significantly different from day 0 (<italic>P</italic> < 0.05).</p> </sec> <sec id="ajd12179-sec-0004" sec-type="section"> <title>Conclusions</title> <p>These findings indicate that treatment with a heparinoid‐containing moisturiser together with a bed bath is an effective method for treating patients who have senile xerosis and IDL.</p> </sec> </abstract>