Primary granulocytic sarcoma of larynx. Issue 3 (13th November 2014)

• Record Type: Journal Article
• Authors: Kim, Luke Y.; Purkey, Michael T.; Patel, Mihir R.; Ghosh, Ankona; Hartner, Lee; Newman, Jason G.; Chen, Amy
• Is Part Of: Head & neck. Volume 37:Issue 3(2015:Mar.)
• Page Start: E38
• Page End: E44
• Publication Date: 2014-11-13
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23805
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="hed23805-sec-0001" sec-type="section"> <title>Background</title> <p>Granulocytic sarcoma is an extramedullary tumor of myeloblasts. The purpose of this report was to present a case of a primary laryngeal granulocytic sarcoma and review of the literature.</p> </sec> <sec id="hed23805-sec-0002" sec-type="section"> <title>Methods</title> <p>A literature review was performed using Medline and PubMed databases to search for cases of all primary and secondary myelogenous tumors of the larynx.</p> </sec> <sec id="hed23805-sec-0003" sec-type="section"> <title>Results</title> <p>A 36‐year‐old man presented with a mass involving the preepiglottic space that was histologically confirmed as an extramedullary acute myeloid leukemia, or granulocytic sarcoma. Our review found 18 cases of secondary involvement of the larynx by myelogenous tumors, and only 1 previously reported case of primary laryngeal granulocytic sarcoma.</p> </sec> <sec id="hed23805-sec-0004" sec-type="section"> <title>Conclusion</title> <p>The detection of granulocytic sarcoma is difficult given its rarity and nonspecific presentation. To our knowledge, this is the second reported case of primary granulocytic sarcoma of the larynx reported in the literature. © 2014 Wiley Periodicals, Inc. <italic>Head Neck</italic> 37: E38–E44, 2015</p> </sec> </abstract>