Prognostic quality of the Union Internationale Contre le Cancer/American Joint Committee on Cancer TNM classification, 7th edition, for cancer of the maxillary sinus. Issue 3 (20th June 2014)

• Record Type: Journal Article
• Authors: Kreppel, Matthias; Amir Manawi, Nilofar‐Natalie; Scheer, Martin; Nickenig, Hans‐Joachim; Rothamel, Daniel; Dreiseidler, Timo; Drebber, Uta; Zinser, Max; Zöller, Joachim E.; Guntinas–Lichius, Orlando; Preuss, Simon Florian
• Is Part Of: Head & neck. Volume 37:Issue 3(2015:Mar.)
• Page Start: 400
• Page End: 406
• Publication Date: 2014-06-20
• Subjects: Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23612
• Languages: English
• ISSNs: 1043-3074

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="hed23612-sec-0001" sec-type="section"> <title>Background</title> <p>Carcinomas of the maxillary sinus are classified according to the Union Internationale Contre le Cancer (UICC)/American Joint Committee on Cancer (AJCC) TNM classification. The purpose of this study was to assess the prognostic significance of the UICC/AJCC TNM classification seventh edition, which was introduced in 2010.</p> </sec> <sec id="hed23612-sec-0002" sec-type="section"> <title>Methods</title> <p>One hundred thirteen patients with malignant tumors of the maxillary sinus were included in this study. The prognostic impact of the TNM classification and the UICC/AJCC seventh edition's stage grouping were analyzed in univariate and multivariate analysis.</p> </sec> <sec id="hed23612-sec-0003" sec-type="section"> <title>Results</title> <p>The UICC/AJCC stage grouping, the T classification, and the N classification had a significant impact on overall survival (OS) in univariate analysis (<italic>p</italic> < .05). No significant differences were observed between the groups T4a and T4b (<italic>p</italic> = .109). In multivariate analysis, the UICC/AJCC stage grouping (<italic>p</italic> = .031), the N classification (<italic>p</italic> = .014), and age (<italic>p</italic> < .001) had a significant impact on OS.</p> </sec> <sec id="hed23612-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Although UICC/AJCC stage grouping and the N classification provided a significant prediction of OS in univariate and multivariate analysis, T classification only influenced OS in univariate analysis. © 2014 Wiley Periodicals, Inc. <italic>Head Neck</italic> 37: 400–406, 2015</p> </sec> </abstract>