Meta‐analysis of prospective studies on the effects of nut consumption on hypertension and type 2 diabetes mellitus 对食用坚果对高血压和2型糖尿病的影响的前瞻性研究进行的meta分析. (29th July 2014)

• Record Type: Journal Article
• Authors: Guo, Kai; Zhou, Zhiwen; Jiang, Yibo; Li, Wei; Li, Yigang
• Is Part Of: Journal of diabetes. Volume 7:Number 2(2015:Apr.)
• Page Start: 202
• Page End: 212
• Publication Date: 2014-07-29
• Subjects: Diabetes -- Periodicals; 618.3646005
• DOI: 10.1111/1753-0407.12173
• Languages: English
• ISSNs: 1753-0393

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jdb12173-sec-0001" sec-type="section"> <title>Background</title> <p>Inconclusive reports have been published on the consumption of nuts and the risk of hypertension and type 2 diabetes mellitus (T2DM). We performed a meta‐analysis of prospective studies to assess the effects of nut consumption on hypertension and T2DM risks.</p> </sec> <sec id="jdb12173-sec-0002" sec-type="section"> <title>Methods</title> <p>A PUBMED and EMBASE database search was performed. Summary relative risks (SRRs) and 95% confidence intervals (CIs) were calculated using a random‐effects model. Q and I<sup>2</sup> statistics were used to examine between‐study heterogeneity.</p> </sec> <sec id="jdb12173-sec-0003" sec-type="section"> <title>Results</title> <p>A total of eight articles with nine prospective cohort studies (three hypertension studies and six T2DM studies) were selected. Using random effects models, we found that compared with never/rare consumers of nuts, those consuming >2 servings per week had an 8% lower risk of hypertension (SRR = 0.92, 95% CI: 0.87–0.97, P<sub> heterogeneity</sub> = 0. 590, I<sup>2</sup> = 0%), while consumption of nuts at one serving per week had similar risk (SRR = 0.97, 95% CI: 0.83–1.13). In addition, nuts consumption was not associated with risk of T2DM (SRRs = 0. 98, 95% CI: 0.84–1.15; P<sub>heterogeneity</sub> = 0. 008, I<sup>2</sup> = 67.7%) on the basis of the highest versus lowest analysis. This null association was also shown in the dose‐response analysis.</p> </sec> <sec id="jdb12173-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Findings from this meta‐analysis indicate that consumption of nuts (>2 servings/week) may be inversely associated with hypertension risk, but not with T2DM risk.</p> </sec> </abstract>