Thermoresponsive poly(ϵ‐caprolactone)‐graft‐poly(N‐isopropylacrylamide) graft copolymers prepared by a combination of ring‐opening polymerization and sequential azide–alkyne click chemistry. Issue 3 (15th September 2014)

• Record Type: Journal Article
• Authors: Li, Mingming; Pan, Pengju; Shan, Guorong; Bao, Yongzhong
• Is Part Of: Polymer international. Volume 64:Issue 3(2015:Mar.)
• Page Start: 389
• Page End: 396
• Publication Date: 2014-09-15
• Subjects: Plastics -- Periodicals; Polymers -- Periodicals; Polymerization -- Periodicals; 547.7
• DOI: 10.1002/pi.4800
• Languages: English
• ISSNs: 0959-8103

Abstract

<abstract abstract-type="graphical" id="pi4800-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p id="pi4800-para-0001">A straightforward strategy is described to synthesize poly(<italic>ϵ</italic>‐caprolactone)‐<italic>graft</italic>‐poly(<italic>N</italic>‐isopropylacrylamide) (PCL‐<italic>g</italic>‐PNIPAAm) amphiphilic graft copolymers consisting of potentially biodegradable polyester backbone and thermoresponsive grafting chains via a combination of ring‐opening polymerization, atom transfer radical polymerization and azide–alkyne click chemistry. PCL‐<italic>g</italic>‐PNIPAAm graft copolymers self‐assemble into thermosensitive micelles in aqueous solution. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh3r5jrq9c" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>