Chronic respiratory failure due to toxic epidermal necrosis in a 10 year old girl. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Thimmesch, M.; Gilbert, A.; Tuerlinckx, D.; Bodart, E.
• Is Part Of: Acta clinica belgica. Volume 70:Issue 1(2015)
• Page Start: 69
• Page End: 71
• Publication Date: 2015-02
• Subjects: Clinical medicine -- Periodicals; Diagnosis, Laboratory -- Periodicals; 616.005
• DOI: 10.1179/2295333714Y.0000000086
• Languages: English
• ISSNs: 1784-3286

Abstract

<abstract> <title> <x content-type="archive" xml:space="preserve">Abstract</x> </title> <p>Toxic epidermal necrosis is a severe mucocutaneous disease with a high mortality rate. A third of the patients surviving the acute phase will develop pulmonary complications. The most frequent complication is bronchiolitis obliterans. Despite well-conducted treatment, in most cases, lung injury often leads to chronic respiratory failure. We describe here the case of a young patient that presented a toxic epidermal necrosis at the age of 3 years. Poor therapeutic compliance result in chronic respiratory failure and after 7 years of follow-up, pulmonary transplant remains the only long-term alternative. Close monitoring of respiratory symptoms in the course of toxic epidermal necrosis, intense treatment as soon as they appear and a long-term follow-up are essential to postpone chronic respiratory failure.</p> </abstract>