Rhodium‐Catalyzed Asymmetric Synthesis of Silicon‐Stereogenic Dibenzosiloles by Enantioselective [2+2+2] Cycloaddition1. (9th December 2014)

• Record Type: Journal Article
• Authors: Shintani, Ryo; Takagi, Chihiro; Ito, Tomoaki; Naito, Masanobu; Nozaki, Kyoko
• Is Part Of: Angewandte Chemie. Volume 127:Number 5(2015)
• Page Start: 1636
• Page End: 1640
• Publication Date: 2014-12-09
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201409733
• Languages: English
• ISSNs: 0044-8249

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A rhodium‐catalyzed asymmetric synthesis of silicon‐stereogenic dibenzosiloles has been developed through a [2+2+2] cycloaddition of silicon‐containing prochiral triynes with internal alkynes. High yields and enantioselectivities have been achieved by employing an axially chiral monophosphine ligand, and the present catalysis is also applicable to the asymmetric synthesis of a germanium‐stereogenic dibenzogermole. Preliminary studies on the optical properties of these compounds are also described.</p> </abstract>