Macronutrient intake and type 2 diabetes risk in middle-aged Australian women. Results from the Australian Longitudinal Study on Women's Health. Issue 7 (18th July 2013)

• Record Type: Journal Article
• Authors: Alhazmi, Amani; Stojanovski, Elizabeth; McEvoy, Mark; Garg, Manohar L
• Is Part Of: Public health nutrition. Volume 17:Issue 7(2014)
• Page Start: 1587
• Page End: 1594
• Publication Date: 2013-07-18
• Subjects: Nutrition -- Periodicals; Nutrition policy -- Periodicals; Public health -- Periodicals; 613.2
• DOI: 10.1017/S1368980013001870
• Languages: English
• ISSNs: 1368-9800

Abstract

<abstract abstract-type="normal"> <title>Abstract</title> <sec id="abs1" sec-type="general"> <title>Objective</title> <p>To investigate the association between macronutrient intake and type 2 diabetes risk in middle-aged Australian women.</p> </sec> <sec id="abs2" sec-type="general"> <title>Design</title> <p>A prospective cohort study, with 6 years (2002–2007) of follow up. Dietary intake was assessed with a validated FFQ. Relative risks with 95 % confidence intervals were used to examine risk associations.</p> </sec> <sec id="abs3" sec-type="general"> <title>Setting</title> <p>Australian Longitudinal Study on Women's Health, Australia.</p> </sec> <sec id="abs4" sec-type="subjects"> <title>Subjects</title> <p>Australian women (<italic>n</italic> 8370) from the Australian Longitudinal Study on Women's Health aged 45–50 years and free of type 2 diabetes at baseline.</p> </sec> <sec id="abs5" sec-type="results"> <title>Results</title> <p>After 6 years of follow-up, 311 women developed type 2 diabetes. After adjusting for sociodemographic, lifestyle and other dietary risk factors, MUFA, total <italic>n</italic>-3 PUFA, α-linolenic acid and total <italic>n</italic>-6 PUFA intakes were positively associated with the incidence of type 2 diabetes. The relative risks for type 2 diabetes for the highest compared with the lowest quintiles were 1·64 (95 % CI 1·06, 2·54), <italic>P</italic> = 0·04 for MUFA; 1·55 (95 % CI 1·03, 2·32), <italic>P</italic> = 0·01 for <italic>n</italic>-3 PUFA; 1·84 (95 % CI 1·25, 2·71), <italic>P</italic> < 0·01 for α-linolenic acid; and 1·60 (95 % CI 1·03, 2·48), <italic>P</italic> = 0·04 for <italic>n</italic>-6 PUFA. Other dietary macronutrients were not significantly associated with diabetes risk.</p> </sec> <sec id="abs6" sec-type="conclusion"> <title>Conclusions</title> <p>The data indicate that consumption of MUFA, <italic>n</italic>-3 PUFA and <italic>n</italic>-6 PUFA may influence the risk of developing type 2 diabetes in women.</p> </sec> </abstract>