A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial. Issue 3 (4th March 2013)

• Record Type: Journal Article
• Authors: Stuart, Keren Louise; Wyld, Belinda; Bastiaans, Kathryn; Stocks, Nigel; Brinkworth, Grant; Mohr, Phil; Noakes, Manny
• Is Part Of: Public health nutrition. Volume 17:Issue 3(2014)
• Page Start: 640
• Page End: 647
• Publication Date: 2013-03-04
• Subjects: Nutrition -- Periodicals; Nutrition policy -- Periodicals; Public health -- Periodicals; 613.2
• DOI: 10.1017/S1368980013000220
• Languages: English
• ISSNs: 1368-9800

Abstract

<abstract abstract-type="normal"> <title>Abstract</title> <sec id="abs1" sec-type="general"> <title>Objective</title> <p>To evaluate a primary prevention care model using telephone support delivered through an existing health call centre to general practitioner-referred patients at risk of developing CVD, using objective measures of CVD risk reduction and weight loss.</p> </sec> <sec id="abs2" sec-type="general"> <title>Design</title> <p>Participants were randomised into two groups: (i) those receiving a telephone-supported comprehensive lifestyle intervention programme (CLIP: written structured diet and exercise advice, plus seven telephone sessions with the Heart Foundation Health Information Service); and (ii) those receiving usual care from their general practitioner (control: written general lifestyle advice). Fasting plasma lipids, blood pressure, weight, waist circumference and height were assessed on general practice premises by a practice nurse at Weeks 0 and 12.</p> </sec> <sec id="abs3" sec-type="general"> <title>Setting</title> <p>Two general practices in Adelaide, South Australia.</p> </sec> <sec id="abs4" sec-type="subjects"> <title>Subjects</title> <p>Forty-nine men and women aged 48·0 (<sc>sd</sc> 5·88) years identified by their general practitioner as being at future risk of CVD (BMI = 33·13 (<sc>sd</sc> 5·39) kg/m<sup>2</sup>; LDL cholesterol (LDL-C) = 2·66 (<sc>sd</sc> 0·92) mmol/l).</p> </sec> <sec id="abs5" sec-type="results"> <title>Results</title> <p>CLIP participants demonstrated significantly greater reductions in LDL-C (estimated mean (<sc>EM)</sc> = 1·98 (<sc>se</sc> 0·17) mmol/l) and total cholesterol (EM = 3·61 (<sc>se</sc> 0·21) mmol/l) at Week 12 when compared with the control group (EM = 3·23 (<sc>se</sc> 0·18) mmol/l and EM = 4·77 (<sc>se</sc> 0·22) mmol/l, respectively). There were no significant treatment effects for systolic blood pressure (<italic>F</italic>(1, 45) = 0·28, <italic>P</italic> = 0·60), diastolic blood pressure (<italic>F</italic>(1, 43) = 0·52, <italic>P</italic> = 0·47), weight (<italic>F</italic>(1, 42) = 3·63, <italic>P</italic> = 0·063) or waist circumference (<italic>F</italic>(1, 43) = 0·32, <italic>P</italic> = 0·577).</p> </sec> <sec id="abs6" sec-type="conclusion"> <title>Conclusions</title> <p>In general practice patients, delivering CLIP through an existing telephone health service is effective in achieving reductions in LDL-C and total cholesterol. While CLIP may have potential for wider implementation to support primary prevention of CVD, longer-term cost-effectiveness data are warranted.</p> </sec> </abstract>