Transporter Studies in Drug Development: Experience to Date and Follow‐Up on Decision Trees From the International Transporter Consortium. Issue 1 (10th April 2013)

• Record Type: Journal Article
• Authors: Tweedie, D; Polli, J W; Berglund, E Gil; Huang, S M; Zhang, L; Poirier, A; Chu, X; Feng, B; International Transporter Consortium
• Is Part Of: Clinical pharmacology & therapeutics. Volume 94:Issue 1(2013)
• Page Start: 113
• Page End: 125
• Publication Date: 2013-04-10
• Subjects: Pharmacology -- Periodicals; Therapeutics -- Periodicals; 615.5
• DOI: 10.1038/clpt.2013.77
• Languages: English
• ISSNs: 0009-9236

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The International Transporter Consortium (ITC) organized a second workshop in March 2012 to expand on the themes developed during the inaugural ITC workshop held in 2008. The final session of the workshop provided perspectives from regulatory and industry‐based scientists, with input from academic scientists, and focused primarily on the decision trees published from the first workshop. These decision trees have become a central part of subsequent regulatory drug–drug interaction (DDI) guidances issued over the past few years.</p> <p> <italic>Clinical Pharmacology &amp; Therapeutics</italic> (2013); <bold>94</bold> 1, 113–125. doi:<ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">10.1038/clpt.2013.77</ext-link></p> </abstract>