Anchoring Group Effects of Surface Ligands on Magnetic Properties of Fe3O4 Nanoparticles: Towards High Performance MRI Contrast Agents. (24th February 2014)

• Record Type: Journal Article
• Authors: Zeng, Jianfeng; Jing, Lihong; Hou, Yi; Jiao, Mingxia; Qiao, Ruirui; Jia, Qiaojuan; Liu, Chunyan; Fang, Fang; Lei, Hao; Gao, Mingyuan
• Is Part Of: Advanced materials. Volume 26:Number 17(2014)
• Page Start: 2694
• Page End: 2698
• Publication Date: 2014-02-24
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201304744
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adma201304744-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The effect of the anchoring group of surface ligands</bold> on the magnetic properties, especially relaxometric properties, of PEGylated Fe₃O₄ nanoparticles is investigated. Systematic experimental results together with in‐depth theoretical analysis reveal that the ligand binding affinity can largely vary the saturation magnetization, whereas conjugated anchoring groups can remarkably enhance the transverse relaxivity, which highlights a novel approach for achieving high‐performance MRI contrast agents. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg5nnfxv5b" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>