Efficacy of Acitretin for Porokeratosis in a Child with Chronic Cutaneous Graft Versus Host Disease. Issue 1 (16th November 2011)

• Record Type: Journal Article
• Authors: Borroni, Riccardo G.; Poddighe, Dimitri; Zecca, Marco; Brazzelli, Valeria
• Is Part Of: Pediatric dermatology. Volume 30:Issue 1(2013)
• Page Start: 148
• Page End: 150
• Publication Date: 2011-11-16
• Subjects: Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/j.1525-1470.2011.01610.x
• Languages: English
• ISSNs: 0736-8046

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Abstract: </bold> Porokeratosis is a rare disorder of epidermal keratinization that is regarded as a precancerous. Recipients of hematopoietic stem cell transplantation (HSCT) have a greater risk of skin cancer; chronic graft versus host disease (GVHD) is an additional risk factor. A 16‐year‐old boy who had received HSCT for acute myelogenous leukemia was referred to us for sclerodermoid chronic cutaneous GVHD. Two years later, he developed disseminated porokeratosis with a few atypical lesions. Despite cryotherapy, numerous lesions of porokeratosis recurred rapidly. Acitretin resulted in good clinical response and reduced the rate of onset of new lesions.</p> </abstract>