Assessment of Left Atrial Function after Percutaneous Closure of Patent Foramen Ovale. Issue 7 (24th January 2013)

• Record Type: Journal Article
• Authors: Vavuranakis, Manolis; Kavouras, Charalampos; Vlasseros, Ioannis; Aggeli, Constantina; Felekos, Ioannis; Vrachatis, Dimitrios A.; Stefanadis, Christodoulos
• Is Part Of: Echocardiography. Volume 30:Issue 7(2013)
• Page Start: 765
• Page End: 771
• Publication Date: 2013-01-24
• Subjects: Echocardiography -- Periodicals; Echocardiography -- Periodicals; 616.1207543
• DOI: 10.1111/echo.12123
• Languages: English
• ISSNs: 0742-2822

Abstract

<abstract abstract-type="main" xml:lang="en" id="echo12123-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="echo12123-sec-0001" sec-type="section"> <title>Background</title> <p>Τhe influence of atrial septal occluders in left atrial (LA) function after percutaneous closure of patent foramen ovale (PFO) has not been thoroughly studied.</p> </sec> <sec id="echo12123-sec-0002" sec-type="section"> <title>Methods</title> <p>Twenty‐five patients (mean age 40.7 ± 12 years) undergoing percutaneous PFO closure were enrolled in this study. Transthoracic echocardiogram (TTE) was performed 3 and 6 months before the procedure. Volumetric indices (active emptying fraction: LA AEF, expansion index: LA EI, and passive emptying fraction: LA PEF), strain and strain rate (SR), were calculated during the contractile, reservoir, and conduit LA phases for the lateral, anterior, and inferior LA walls with TTE.</p> </sec> <sec id="echo12123-sec-0003" sec-type="section"> <title>Results</title> <p>After 3 months, a decrease in the SR of the LA anterior wall was observed (from 2.12 ± 0.22 to 1.66 ± 0.26, P < 0.045), while the LA lateral wall strain was found to be increased (from 0.708 ± 0.15 to 0.783 ± 0.159, P < 0.001). Moreover, simultaneously LA AEF was greater compared with baseline (from 31.0 ± 1.6 to 34.0 ± 1.6, P < 0.004). However, all these alterations reversed at 6 months.</p> </sec> <sec id="echo12123-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Segmental LA function is altered transiently after percutaneous PFO closure with a septal occlude. The LA anterior wall SR decreases, while the lateral wall strain increases. The impact of these alterations needs further clarification.</p> </sec> </abstract>