Enzyme‐Free Unlabeled DNA Logic Circuits Based on Toehold‐Mediated Strand Displacement and Split G‐Quadruplex Enhanced Fluorescence. (28th February 2013)

• Record Type: Journal Article
• Authors: Zhu, Jinbo; Zhang, Libing; Li, Tao; Dong, Shaojun; Wang, Erkang
• Is Part Of: Advanced materials. Volume 25:Number 17(2013)
• Page Start: 2440
• Page End: 2444
• Publication Date: 2013-02-28
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201205360
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Adopting fluorescence of PPIX enhanced by a split G‐quadruplex and toehold mediated strand displacement reaction</bold>, a series of unlabeled fluorescent logic gates is set up and some of them are cascaded into circuits. Controlled release of PPIX, which is also a photosensitizer in photodynamic diagnosis and therapy, is realized by this circuit, making it a wise choice for DNA computing. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1zskf39w" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>