Single Continuous Wave Laser Induced Photodynamic/Plasmonic Photothermal Therapy Using Photosensitizer‐Functionalized Gold Nanostars. (13th February 2013)

• Record Type: Journal Article
• Authors: Wang, Shouju; Huang, Peng; Nie, Liming; Xing, Ruijun; Liu, Dingbin; Wang, Zhe; Lin, Jing; Chen, Shouhui; Niu, Gang; Lu, Guangming; Chen, Xiaoyuan
• Is Part Of: Advanced materials. Volume 25:Number 22(2013)
• Page Start: 3055
• Page End: 3061
• Publication Date: 2013-02-13
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201204623
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Chlorin e6 conjugated gold nanostars (GNS‐PEG‐Ce6)</bold> are used to perform simultaneous photodynamic/plasmonic photothermal therapy (PDT/PPTT) upon single laser irradiation. The early‐phase PDT effect is coordinated with the late‐phase PPTT effect to obtain synergistic anticancer efficiency. The prepared GNS‐PEG‐Ce6 shows excellent water dispersibility, good biocompatibility, enhanced cellular uptake and remarkable anticancer efficiency upon irradiation in vivo. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg21kq65t7" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>