Cover Picture: Cascade Syntheses Routes to the Centrocountins (Chem. Eur. J. 7/2013). Issue 7 (1st February 2013)

• Record Type: Journal Article
• Authors: Eschenbrenner‐Lux, Vincent; Dückert, Heiko; Khedkar, Vivek; Bruss, Hanna; Waldmann, Herbert; Kumar, Kamal
• Is Part Of: Chemistry. Volume 19:Issue 7(2013)
• Page Start: 2197
• Page End: 2197
• Publication Date: 2013-02-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201390017
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The longest cascade reaction sequence known to date provides natural‐product‐inspired and biologically active centrocountins, or tetrahydroindoloquinolizines and related molecules. K. Kumar, H. Waldmann et al. unravel mechanistic insights into this long cascade reaction sequence in their Full Paper on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 2294 ff.</ext-link> by isolating and characterizing various intermediates and with control experiments. The cover picture shows a natural setup as a symbolic source of inspiration. As the reaction substrates in the pool of water flow in different streams, representing different cascade reaction sequences, they are progressively transformed into different intermediates before settling as a collection of products, the tetrahydro(indolo)quinolizine molecules.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1v4frs2x" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>