Efficient Synthesis of Cyclopropane‐Fused Heterocycles with Bromoethylsulfonium Salt. Issue 33 (10th July 2013)

• Record Type: Journal Article
• Authors: Fritz, Sven P.; Matlock, Johnathan V.; McGarrigle, Eoghan M.; Aggarwal, Varinder K.
• Is Part Of: Chemistry. Volume 19:Issue 33(2013)
• Page Start: 10827
• Page End: 10831
• Publication Date: 2013-07-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201302081
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Lord of the rings!</bold> [3.1.0] bicyclic ring systems were synthesized using bromoethylsulfonium triflate and easily available amino acid/aza‐Morita–Baylis–Hillman‐derived allylic amines. The simple transformation displays a very high degree of diastereoselectivity and enables access to a diverse range of densely substituted pyrrolidine‐based bicycles.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36r2sj60" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>