More than Meets the Eye: Conformational Switching of a Stacked Dialkoxynaphthalene–Naphthalenetetracarboxylic diimide (DAN–NDI) Foldamer to an NDI–NDI Fibril Aggregate. Issue 35 (12th July 2013)

• Record Type: Journal Article
• Authors: Peebles, Cameron; Piland, Rebecca; Iverson, Brent L.
• Is Part Of: Chemistry. Volume 19:Issue 35(2013)
• Page Start: 11598
• Page End: 11602
• Publication Date: 2013-07-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201302009
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The thermally induced conformational switching of a stacked dialkxoynaphthalene–naphthalenetetracarboxylic diimide (DAN–NDI) amphiphilic foldamer to an NDI–NDI fibril aggregate is described. The aggregated fibril structures were explored by UV/Vis, circular dichroism (CD), atomic‐force microscopy (AFM), and TEM techniques. Our findings indicate that the aromatic DAN–NDI interactions of the original foldamer undergoes transformation to a fibrillar assembly with aromatic NDI–NDI stacked interactions. These structural insights could help inform new molecular designs and increase our understanding of fibrillar assembly and aggregation process in aqueous solution.</p> </abstract>