Synthesis and Structural Characterization of Hexacoordinate Silicon, Germanium, and Titanium Complexes of the E. coli Siderophore Enterobactin. Issue 32 (2nd July 2013)

• Record Type: Journal Article
• Authors: Baramov, Todor; Keijzer, Karlijn; Irran, Elisabeth; Mösker, Eva; Baik, Mu‐Hyun; Süssmuth, Roderich
• Is Part Of: Chemistry. Volume 19:Issue 32(2013)
• Page Start: 10536
• Page End: 10542
• Publication Date: 2013-07-02
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201301825
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The <italic>E. coli</italic> siderophore enterobactin, one of the strongest Fe^III chelators known to date, is also capable of binding Si^IV under physiological conditions. We report on the synthesis and structural characterization of the tris(catecholate) Si^IV–enterobactin complex and its Ge^IV and Ti^IV analogues. Comparative structural analysis, supported by quantum‐chemical calculations, reveals the correlation between the ionic radius and the structural changes in enterobactin upon complexation.</p> </abstract>