A Hybrid Ring‐Opening Metathesis Polymerization Catalyst Based on an Engineered Variant of the β‐Barrel Protein FhuA. Issue 41 (19th August 2013)

• Record Type: Journal Article
• Authors: Philippart, Freddi; Arlt, Marcus; Gotzen, Steve; Tenne, Stefanie‐Joana; Bocola, Marco; Chen, Hsui‐Hui; Zhu, Leilei; Schwaneberg, Ulrich; Okuda, Jun
• Is Part Of: Chemistry. Volume 19:Issue 41(2013)
• Page Start: 13865
• Page End: 13871
• Publication Date: 2013-08-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201301515
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A β‐barrel protein hybrid catalyst was prepared by covalently anchoring a Grubbs–Hoveyda type olefin metathesis catalyst at a single accessible cysteine amino acid in the barrel interior of a variant of β‐barrel transmembrane protein <italic>ferric hydroxamate uptake protein component A</italic> (FhuA). Activity of this hybrid catalyst type was demonstrated by ring‐opening metathesis polymerization of a 7‐oxanorbornene derivative in aqueous solution.</p> </abstract>