A Survey of Sulfide Ligands for Allylic CH Oxidations of Terminal Olefins. Issue 34 (9th July 2013)

• Record Type: Journal Article
• Authors: Le, Chi "Chip"; Kunchithapatham, Kamala; Henderson, William H.; Check, Christopher T.; Stambuli, James P.
• Is Part Of: Chemistry. Volume 19:Issue 34(2013)
• Page Start: 11153
• Page End: 11157
• Publication Date: 2013-07-09
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201301787
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Perfect to a THT!</bold> Screening a diverse library of thioether ligands led to the discovery of tetrahydrothiophene (THT) as a highly reactive and selective ligand for Pd‐catalyzed allylic CH oxidation reactions (see scheme). This novel ligand system provides some of the highest reported yields for the formation of (<italic>E</italic>)‐linear allylic acetates through allylic CH activation chemistry (BQ = 1, 4‐benzoquinone).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36r493r7" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>