A Molecularly Defined Iron‐Catalyst for the Selective Hydrogenation of α, β‐Unsaturated Aldehydes. Issue 24 (6th May 2013)

• Record Type: Journal Article
• Authors: Wienhöfer, Gerrit; Westerhaus, Felix A.; Junge, Kathrin; Ludwig, Ralf; Beller, Matthias
• Is Part Of: Chemistry. Volume 19:Issue 24(2013)
• Page Start: 7701
• Page End: 7707
• Publication Date: 2013-05-06
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201300660
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A selective iron‐based catalyst system for the hydrogenation of α, β‐unsaturated aldehydes to allylic alcohols is presented. Applying the defined iron–tetraphos complex [FeF(L)][BF₄] (L=P(PhPPh₂)₃) in the presence of trifluoroacetic acid a broad range of aldehydes are reduced in high yields using low catalyst loadings (0.05–1 mol %). Excellent chemoselectivity for the reduction of aldehydes in the presence of other reducible moieties, for example, ketones, olefins, esters, etc. is achieved. Based on the in situ detected hydride species [FeH(H₂)(L)]⁺ a catalytic cycle is proposed that is supported by computational calculations.</p> </abstract>