A Concise Synthesis of L‐Pyrrolysine1. Issue 25 (3rd May 2013)

• Record Type: Journal Article
• Authors: Han, Man‐Yi; Wang, Huai‐Zhen; An, Wan‐Kai; Jia, Ju‐Ying; Ma, Bao‐Chun; Zhang, Yuan; Wang, Wei
• Is Part Of: Chemistry. Volume 19:Issue 25(2013)
• Page Start: 8078
• Page End: 8081
• Publication Date: 2013-05-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201300403
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Organocatalysis</bold>: A concise synthesis of <sc>L</sc>‐pyrrolysine has been accomplished in six steps from simple starting materials. The facile synthetic strategy relies on an organocatalytic Michael addition, an efficient amide coupling, and a challenging method for the imine‐bond construction (see scheme).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg21kvs9t9" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>