Cascade Hydroamination/Redox Reaction for the Synthesis of Cyclic Aminals Catalyzed by a Combined Gold Complex and Brønsted Acid. Issue 17 (19th March 2013)

• Record Type: Journal Article
• Authors: He, Yu‐Ping; Wu, Hua; Chen, Dian‐Feng; Yu, Jie; Gong, Liu‐Zhu
• Is Part Of: Chemistry. Volume 19:Issue 17(2013)
• Page Start: 5232
• Page End: 5237
• Publication Date: 2013-03-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201300052
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Relay catalysis</bold>: An unprecedented protocol for the synthesis of cyclic aminals has been realized under the relay catalysis of a gold(I)/Brønsted acid binary system to generate cyclic aminals in excellent yields of up to 99 % with moderate to high diastereoselectivity (see scheme; up to 95:5 d.r.).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1xq2bgtg" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>