Antagonism of antifungal metabolites from Streptomyces griseus H7602 against Phytophthora capsici. (19th February 2014)

• Record Type: Journal Article
• Authors: Nguyen, Xuan Hoa; Naing, Kyaw Wai; Lee, Young Seong; Kim, Yong Hwan; Moon, Jae Hak; Kim, Kil Yong
• Is Part Of: Journal of basic microbiology. Volume 55:issue 1(2015:Jan.)
• Page Start: 45
• Page End: 53
• Publication Date: 2014-02-19
• Subjects: Microbiology -- Periodicals; 579
• DOI: 10.1002/jobm.201300820
• Languages: English
• ISSNs: 0233-111X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jobm201300820-sec-0001" sec-type="section"> <p>In this study, evidences for antagonism were established by production of antifungal metabolites from <italic>Streptomyces griseus</italic> H7602, which were active to inhibit mycelial growth of <italic>Phytophthora capsici</italic> in the <italic>in vitro</italic> assays. Mycelial growth and zoosporangia formation of <italic>P. capsici</italic> was strongly inhibited in the medium containing the cell free culture filtrate of <italic>S. griseus</italic> H7602. Antifungal metabolites from the cell free culture filtrate of <italic>S. griseus</italic> H7602 showed substantial antagonistic effects on <italic>P. capsici</italic>. In addition, a purified antifungal compound was separated from the antifungal metabolites of <italic>S. griseus</italic> H7602 and identified to be 1<italic>H</italic>‐pyrrole‐2‐carboxylic acid (PCA) by spectra analyses. PCA showed strong antifungal activity and was evaluated for the first time for its antagonism against <italic>P. capsici</italic> under <italic>in vitro</italic> conditions. Minimum inhibitory concentration (MIC) value of PCA was low (4 µg ml<sup>−1</sup>), and the mycelial growth of <italic>P. capsici</italic> was almost inhibited at concentration of 64 µg ml<sup>−1</sup>. This study suggests that the PCA may be useful as biofungicides against <italic>P. capsici</italic>, and the prominent antagonism of antifungal metabolites from <italic>S. griseus</italic> H7602 highlights it as a candidate for biocontrol of <italic>P. capsici</italic>.</p> </sec> </abstract>