"Nanorust"‐catalyzed Benign Oxidation of Amines for Selective Synthesis of Nitriles. Issue 1 (24th October 2014)

• Record Type: Journal Article
• Authors: Jagadeesh, Rajenahally V.; Junge, Henrik; Beller, Matthias
• Is Part Of: ChemSusChem. Volume 8:Issue 1(2015:Jan.)
• Page Start: 92
• Page End: 96
• Publication Date: 2014-10-24
• Subjects: Green chemistry -- Periodicals; Sustainable engineering -- Periodicals; Chemistry -- Periodicals; Chemical engineering -- Periodicals; 660
• DOI: 10.1002/cssc.201402613
• Languages: English
• ISSNs: 1864-5631

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Organic nitriles constitute key precursors and central intermediates in organic synthesis. In addition, nitriles represent a versatile motif found in numerous medicinally and biologically important compounds. Generally, these nitriles are synthesized by traditional cyanation procedures using toxic cyanides. Herein, we report the selective and environmentally benign oxidative conversion of primary amines for the synthesis of structurally diverse aromatic, aliphatic and heterocyclic nitriles using a reusable "nanorust" (nanoscale Fe₂O₃)‐based catalysts applying molecular oxygen.</p> </abstract>