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ChemInform Abstract: I2—DMSO Promoted Intramolecular Oxidative Cyclization of 2‐(Aryl or Alkyl Amino)‐acetophenones for the Synthesis of Isatins. Issue 4 (January 2015)
Record Type:
Journal Article
Title:
ChemInform Abstract: I2—DMSO Promoted Intramolecular Oxidative Cyclization of 2‐(Aryl or Alkyl Amino)‐acetophenones for the Synthesis of Isatins. Issue 4 (January 2015)
Main Title:
ChemInform Abstract: I2—DMSO Promoted Intramolecular Oxidative Cyclization of 2‐(Aryl or Alkyl Amino)‐acetophenones for the Synthesis of Isatins.
<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Treatment of acetophenones (I) with iodine in DMSO results in the formation of isatins via a glyoxal intermediate which undergoes intramolecular addition of the amino group to the aldehyde moiety followed by DMSO oxidation.</p> </abstract>