Development of astrocytes in the vertebrate eye. Issue 12 (13th October 2014)

• Record Type: Journal Article
• Authors: Tao, Chenqi; Zhang, Xin
• Is Part Of: Developmental dynamics. Volume 243:Issue 12(2014:Dec.)
• Page Start: 1501
• Page End: 1510
• Publication Date: 2014-10-13
• Subjects: Morphogenesis -- Periodicals; Anatomy -- Periodicals; Anatomie -- Périodiques; Biologie du développement -- Périodiques; 571.833
• DOI: 10.1002/dvdy.24190
• Languages: English
• ISSNs: 1058-8388

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Astrocytes represent the earliest glial population in the embryonic optic nerve, contributing critically to retinal angiogenesis and formation of brain‐retinal‐barrier. Despite of many developmental and clinical implications of astrocytes, answers to some of the most fundamental questions of this unique type of glial cells remain elusive. This review provides an overview of the current knowledge about the origination, proliferation, and differentiation of astrocytes, their journey from the optic nerve toward the neuroretina, and their involvement in physiological and pathological development of the visual system. <italic>Developmental Dynamics 243:1501–1510, 2014</italic>. © 2014 Wiley Periodicals, Inc.</p> </abstract>