A Convenient Fluorescent Method to Simultaneously Determine the Enantiomeric Composition and Concentration of Functional Chiral Amines. Issue 50 (27th October 2014)

• Record Type: Journal Article
• Authors: Huang, Zeng; Yu, Shanshan; Zhao, Xue; Wen, Kaili; Xu, Yimang; Yu, Xiaoqi; Xu, Yong; Pu, Lin
• Is Part Of: Chemistry. Volume 20:Issue 50(2014)
• Page Start: 16458
• Page End: 16461
• Publication Date: 2014-10-27
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201405143
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A 1, 1′‐bi‐2‐naphthol (BINOL)‐based chiral aldehyde in combination with Zn^II shows a highly enantioselective fluorescent response toward functional chiral amines at <italic>λ</italic>&gt;500 nm. However, the combination of salicylaldehyde and Zn^II gives the same fluorescent enhancement for both enantiomers of a functional chiral amine at <italic>λ</italic>=447 nm. By using the fluorescent responses of the combination of the BINOL‐based chiral aldehyde, salicylaldehyde and Zn^II at the two emission wavelengths, both the concentration and enantiomeric composition of functional chiral amines such as amino alcohols, diamines, and amino acids can be simultaneously determined by a single fluorescent measurement. This work provides a simple and convenient method for chiral assay.</p> </abstract>