BODIPY‐Based Oligo(ethylene glycol) Dendrons as Fluorescence Thermometers: When Thermoresponsiveness Meets Intramolecular Electron/Charge Transfer1. Issue 50 (21st October 2014)

• Record Type: Journal Article
• Authors: Wang, Hua; Wu, Yongquan; Tao, Pan; Fan, Xing; Kuang, Gui‐Chao
• Is Part Of: Chemistry. Volume 20:Issue 50(2014)
• Page Start: 16634
• Page End: 16643
• Publication Date: 2014-10-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201404292
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The temperature‐dependent photophysical properties of a series of 4, 4‐difluoro‐4‐bora‐3a, 4a‐diaza‐s‐indacene (BODIPY) derivatives with different oligo(ethylene glycol) (OEG) dendrons were investigated. Weak fluorescence emission was observed for these BODIPY derivatives in dilute solution with low viscosity. BDP‐G0 and BDP‐G1‐TEG exhibit a high quantum yield in viscous glycerol solutions, contrary to the moderate and little fluorescence enhancement for BDP‐G1 and BDP‐G2 under the same conditions. The photoinduced electron transfer (PET) may have quenched the fluorescence, as supported by calculation. Interestingly, the thermoresponsive BODIPY derivatives show heat‐induced luminescence enhancement with a high signal‐to‐noise ratio and their emission maxima are dependent on the structures of branched tri(ethylene glycol) moieties. Finally, preliminary studies on the BODIPY derivatives as intracellular fluorescence indicators in living HeLa cells were carried out.</p> </abstract>