Modeling of plant in vitro cultures: Overview and estimation of biotechnological processes. Issue 1 (26th September 2014)

• Record Type: Journal Article
• Authors: Maschke, Rüdiger W.; Geipel, Katja; Bley, Thomas
• Is Part Of: Biotechnology and bioengineering. Volume 112:Issue 1(2015:Jan.)
• Page Start: 1
• Page End: 12
• Publication Date: 2014-09-26
• Subjects: Biotechnology -- Periodicals; Bioengineering -- Periodicals; 660.6
• DOI: 10.1002/bit.25346
• Languages: English
• ISSNs: 0006-3592

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>ABSTRACT</title> <sec id="bit25346-sec-0001" sec-type="section"> <p>Plant cell and tissue cultivations are of growing interest for the production of structurally complex and expensive plant‐derived products, especially in pharmaceutical production. Problems with up‐scaling, low yields, and high‐priced process conditions result in an increased demand for models to provide comprehension, simulation, and optimization of production processes. In the last 25 years, many models have evolved in plant biotechnology; the majority of them are specialized models for a few selected products or nutritional conditions. In this article we review, delineate, and discuss the concepts and characteristics of the most commonly used models. Therefore, the authors focus on models for plant suspension and submerged hairy root cultures. The article includes a short overview of modeling and mathematics and integrated parameters, as well as the application scope for each model. The review is meant to help researchers better understand and utilize the numerous models published for plant cultures, and to select the most suitable model for their purposes. Biotechnol. Bioeng. 2015;112: 1–12. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>