Role of nuclear Lamin A/C in cardiomyocyte functions. (20th August 2014) - Carmosino, Monica
Review Lamin A/C is a structural protein of the nuclear envelope, highly expressed in contractile tissues such as heart and skeletal muscles. It mediates nuclear–cytoskeletal communication, mechanostransduction and gene regulation. Recent reports suggest also a crucial role in conferring resistance to nuclear envelope in cardiomyocytes and in determining the contractile cell type lineage.