Comparison of Cardiogoniometry and ECG at Rest versus Myocardial Perfusion Scintigraphy. Issue 5 (10th March 2014)

• Record Type: Journal Article
• Authors: Weber, Stefan; Birkemeyer, Ralf; Schultes, Dominik; Grewenig, Walter; Huebner, Thomas
• Is Part Of: Annals of noninvasive electrocardiology. Volume 19:Issue 5(2014:Sep.)
• Page Start: 462
• Page End: 470
• Publication Date: 2014-03-10
• Subjects: Electrocardiography -- Periodicals; Arrhythmia -- Periodicals; 616.1207547
• DOI: 10.1111/anec.12151
• Languages: English
• ISSNs: 1082-720X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="anec12151-sec-0010" sec-type="section"> <title>Background</title> <p>Cardiogoniometry (CGM) is a novel resting electrocardiac method based on computer‐generated three‐dimensional data derived from cardiac potentials. The purpose of this study was to determine CGM's and electrocardiography's (ECG) accuracy for detecting myocardial ischemia and/or lesions in comparison with stress/rest myocardial perfusion scintigraphy (single photon emission computer tomography [SPECT]).</p> </sec> <sec id="anec12151-sec-0020" sec-type="section"> <title>Method</title> <p>A cohort of consecutively enrolled patients (n = 100) with suspected or known coronary artery disease (mean age 67.8 years, 52% female) were examined by CGM and resting ECG before stress/rest myocardial scintigraphy.</p> </sec> <sec id="anec12151-sec-0030" sec-type="section"> <title>Results</title> <p>Pathological scintigraphy findings at adenosine stress perfusion (ASP) and/or rest were conclusively identified in 21 patients. Diagnostic sensitivity was 71% for CGM and 24% for ECG, specificity was 70% for CGM and 95% for ECG. Reversible ischemia was diagnosed in 16 of 21 patients with pathological scintigraphy results. In this subgroup, sensitivity was 67% for CGM and 25% for ECG.</p> </sec> <sec id="anec12151-sec-0040" sec-type="section"> <title>Conclusions</title> <p>At rest, the sensitivity of a CGM significantly surmounts that of a standard 12‐lead ECG for detection of isolated myocardial ischemia or myocardial lesions revealed by scintigraphy/SPECT; specificity is in a reasonable range. CGM's ease of use and its considerable agreement with the results of myocardial scintigraphy, suggests a possible role for patient screening in the primary care setting.</p> </sec> </abstract>