Aldehyde‐Assisted Ruthenium(II)‐Catalyzed CH Oxygenations1. (26th August 2014)

• Record Type: Journal Article
• Authors: Yang, Fanzhi; Rauch, Karsten; Kettelhoit, Katharina; Ackermann, Lutz
• Is Part Of: Angewandte Chemie. Volume 126:Number 42(2014)
• Page Start: 11467
• Page End: 11470
• Publication Date: 2014-08-26
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201405647
• Languages: English
• ISSNs: 0044-8249

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Versatile ruthenium(II) complexes allow for site‐selective CH oxygenations with weakly‐coordinating aldehydes. The challenging CH functionalizations proceed with high chemoselectivity by rate‐determining CH metalation. The new method features an ample substrate scope, which sets the stage for the step‐economical preparation of various bioactive heterocycles.</p> </abstract>