Bifidobacterium animalis ssp. lactis BI07 modulates the tumor necrosis factor alpha‐dependent imbalances of the enterocyte‐associated intestinal microbiota fraction. Issue 2 (14th July 2014)

• Record Type: Journal Article
• Authors: Centanni, Manuela; Turroni, Silvia; Rampelli, Simone; Biagi, Elena; Quercia, Sara; Consolandi, Clarissa; Severgnini, Marco; Brigidi, Patrizia; Candela, Marco
• Is Part Of: FEMS microbiology letters. Volume 357:Issue 2(2014:Aug.)
• Page Start: 157
• Page End: 163
• Publication Date: 2014-07-14
• Subjects: Microbiology -- Periodicals; 579
• DOI: 10.1111/1574-6968.12515
• Languages: English
• ISSNs: 0378-1097

Abstract

<abstract abstract-type="main" id="fml12515-abs-0001"> <title>Abstract</title> <p>Using a previously developed <italic>in vitro</italic> model to characterize the enterocyte‐adherent microbiota fraction, we explored the potential of the probiotic strain <italic>Bifidobacterium animalis</italic> ssp. <italic>lactis </italic>BI07 to modulate the inflammation‐dependent dysbioses of the enterocyte‐adherent microbiota from 12 healthy human donors. According to our findings, <italic>B. animalis</italic> ssp. <italic>lactis </italic>BI07 is effective in limiting the increase of pro‐inflammatory pathobionts on the inflamed mucosal site, supporting the recovery of a mutualistic community.</p> </abstract>