The Molecular Structure of Alzheimer β‐Amyloid Fibrils Formed in the Presence of Phospholipid Vesicles1. (8th May 2014)
- Record Type:
- Journal Article
- Title:
- The Molecular Structure of Alzheimer β‐Amyloid Fibrils Formed in the Presence of Phospholipid Vesicles1. (8th May 2014)
- Main Title:
- The Molecular Structure of Alzheimer β‐Amyloid Fibrils Formed in the Presence of Phospholipid Vesicles1
- Authors:
- Niu, Zheng
Zhao, Weijing
Zhang, Zhengfeng
Xiao, Fanshu
Tang, Xinqi
Yang, Jun - Abstract:
- <abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>β‐amyloid (Aβ) fibrils are the major species involved in Alzheimer's disease (AD). An atomic‐resolution molecular structure of Aβ40 fibrils formed in the presence of lipid vesicles was obtained by using magic angle spinning (MAS) solid‐state NMR spectroscopy. The fibril structures formed in the presence of the lipid vesicles are remarkably different from those formed in solution. These results provide insights into the molecular mechanism of Aβ aggregation in the presence of lipid vesicles.</p> </abstract>
- Is Part Of:
- Angewandte Chemie. Volume 126:Number 35(2014)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 126:Number 35(2014)
- Issue Display:
- Volume 126, Issue 35 (2014)
- Year:
- 2014
- Volume:
- 126
- Issue:
- 35
- Issue Sort Value:
- 2014-0126-0035-0000
- Page Start:
- 9448
- Page End:
- 9451
- Publication Date:
- 2014-05-08
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201311106 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 4001.xml