Long‐term outcome of endoscopic balloon dilation for small bowel strictures in patients with Crohn's disease. Issue 4 (17th February 2014)

• Record Type: Journal Article
• Authors: Hirai, Fumihito; Beppu, Takahiro; Takatsu, Noritaka; Yano, Yutaka; Ninomiya, Kazeo; Ono, Yoichiro; Hisabe, Takashi; Matsui, Toshiyuki
• Is Part Of: Digestive endoscopy. Volume 26:Issue 4(2014:Jul.)
• Page Start: 545
• Page End: 551
• Publication Date: 2014-02-17
• Subjects: Digestive organs -- Diseases -- Periodicals; Digestive organs -- Diseases -- Diagnosis -- Periodicals; Endoscopy -- Periodicals; Digestive System Diseases -- diagnosis -- Periodicals; Digestive System Diseases -- therapy -- Periodicals; Endoscopy -- Periodicals; 616.3
• DOI: 10.1111/den.12236
• Languages: English
• ISSNs: 0915-5635

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="den12236-sec-0001" sec-type="section"> <title>Background and Aim</title> <p>Endoscopic balloon dilation (EBD) is an alternative to surgery for small bowel strictures of patients with Crohn's disease (CD). However, little is known about the long‐term efficacy of EBD. The aim of the present study was to clarify the long‐term outcome of EBD for small bowel strictures in patients with CD.</p> </sec> <sec id="den12236-sec-0002" sec-type="section"> <title>Methods</title> <p>Subjects comprised 65 patients with CD who underwent EBD for small intestinal strictures and were followed up for at least 6 months. All subjects had obstructive symptoms as a result of small bowel strictures. Short‐term success was defined as technical success and the disappearance of obstructive symptoms. The short‐term success rate of EBD, its safety profile, the cumulative surgery‐free rate and the cumulative redilation‐free rate were investigated.</p> </sec> <sec id="den12236-sec-0003" sec-type="section"> <title>Results</title> <p>Short‐term success rate was 80.0% (52/65). Complications were encountered in six of the 65 patients (9.2%). Seventeen patients (26.2%) underwent surgery during the observation period of this study. Cumulative surgery‐free rate after initial EBD was 79% at 2 years and 73% at 3 years, respectively. EBD successful cases showed significantly higher surgery‐free rates than unsuccessful cases (<italic>P</italic> < 0.0001). In 52 of the successful cases, the cumulative redilation‐free rate after initial EBD was 64% at 2 years and 47% at 3 years, respectively.</p> </sec> <sec id="den12236-sec-0004" sec-type="section"> <title>Conclusion</title> <p>EBD for small bowel strictures secondary to CD provides not only short‐term success but also long‐term efficacy. However, the high redilation rate is one of the clinical problems of this procedure.</p> </sec> </abstract>