Evaluation of the Effect of Onlay Mesenteric Flaps on End‐To‐End Jejunojejunostomy Healing in Horses. Issue 4 (1st April 2014)

• Record Type: Journal Article
• Authors: Aristizabal, Fabio A.; Lopes, Marco Aurélio; Silva, Adriana; Avanza, Marcel Ferreira; Nieto, Jorge E.
• Is Part Of: Veterinary surgery. Volume 43:Issue 4(2014)
• Page Start: 479
• Page End: 486
• Publication Date: 2014-04-01
• Subjects: Veterinary surgery -- Periodicals; Veterinary Medicine -- Periodicals; Surgery -- Periodicals; Societies, Medical -- Periodicals; 636.0897
• DOI: 10.1111/j.1532-950X.2014.12120.x
• Languages: English
• ISSNs: 0161-3499

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="vsu12120-sec-0001" sec-type="section"> <title>Objective</title> <p>To evaluate the effect of onlay mesenteric flaps (MFs) with end‐to‐end jejunojejunostomy on stomal diameter, length of jejunum with reduced stomal diameter, abdominal adhesion formation, and healing.</p> </sec> <sec id="vsu12120-sec-0002" sec-type="section"> <title>Study Design</title> <p>Experimental study.</p> </sec> <sec id="vsu12120-sec-0003" sec-type="section"> <title>Animals</title> <p>Healthy adult horses (n = 6).</p> </sec> <sec id="vsu12120-sec-0004" sec-type="section"> <title>Methods</title> <p>Two hand sewn end‐to‐end jejunal anastomoses using a 1 layer simple continuous serosubmucosal suture pattern were performed in each horse ∼2 and 5 m oral to the ileocecal fold. Using a random design for selection anastomosis location (oral or aboral), 1 anastomosis was covered with 2 adjacent onlay MFs secured with interrupted sutures and cyanoacrylate glue. Two weeks later, adhesion formation, stomal diameter, length of reduced jejunal stomal diameter, and healing were evaluated.</p> </sec> <sec id="vsu12120-sec-0005" sec-type="section"> <title>Results</title> <p>Use of onlay MFs decreased stomal diameter (<italic>P</italic> = .05), increased length of reduced peristomal jejunal diameter (<italic>P</italic> = .05), surgical time (<italic>P</italic> = .003), and serosal fibrosis (<italic>P</italic> = .05). No difference was evident for adhesion formation, and degree of inflammation between techniques.</p> </sec> <sec id="vsu12120-sec-0006" sec-type="section"> <title>Conclusion</title> <p>End‐to‐end jejunojejunostomy covered with 2 onlay MFs is not recommended because this technique results in luminal reduction.</p> </sec> </abstract>