What determines human body odour?. Issue 5 (May 2014)
- Record Type:
- Journal Article
- Title:
- What determines human body odour?. Issue 5 (May 2014)
- Main Title:
- What determines human body odour?
- Authors:
- Hamada, Kaoru
Haruyama, Sanehito
Yamaguchi, Takashi
Yamamoto, Kayo
Hiromasa, Kana
Yoshioka, Manabu
Nishio, Daisuke
Nakamura, Motonobu - Abstract:
- <abstract abstract-type="main" id="exd12380-abs-0001"> <title>Abstract</title> <p>Human body odour and earwax type are genetically dependent on a single‐nucleotide polymorphism (SNP) located in the <italic>ABCC11</italic> gene. So far, it still remains to be clear how SNP in the <italic>ABCC11</italic> gene is associated with human malodour. In a recent issue of Experimental Dermatology, Baumann et al. propose one of the underlying molecular pathways. Although one of the amino acid conjugated of the odorants, Cys‐Gly‐3‐methyl‐3‐sulfanylhexanol (3M3SH), was not taken up by the transporter ABCC11, glutathione conjugate of 3MSH (SG‐3MSH) was transported by ABCC11. Moreover, SG‐3MSH was processed to 3M3SH by <italic>γ</italic>‐glutamyl‐transferase 1 (GGT1), which was abundantly expressed in apocrine sweat glands. These findings may pave a way for the pharmacogenetics of human body odour and the development of innovative deodorant products.</p> </abstract>
- Is Part Of:
- Experimental dermatology. Volume 23:Issue 5(2014:May)
- Journal:
- Experimental dermatology
- Issue:
- Volume 23:Issue 5(2014:May)
- Issue Display:
- Volume 23, Issue 5 (2014)
- Year:
- 2014
- Volume:
- 23
- Issue:
- 5
- Issue Sort Value:
- 2014-0023-0005-0000
- Page Start:
- 316
- Page End:
- 317
- Publication Date:
- 2014-05
- Subjects:
- Dermatology -- Periodicals
616.5 - Journal URLs:
- http://www.blackwellpublishing.com/journal.asp?ref=0906-6705&site=1 ↗
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-0625 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1111/exd.12380 ↗
- Languages:
- English
- ISSNs:
- 0906-6705
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3839.070000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 3145.xml