Association between low renal function and tooth loss over 5 years. (26th November 2012)

• Record Type: Journal Article
• Authors: Yoshihara, Akihiro; Iwasaki, Masanori; Miyazaki, Hideo; Nakamura, Kazutoshi
• Is Part Of: Gerodontology. Volume 31:Number 2(2014:Jun.)
• Page Start: 111
• Page End: 116
• Publication Date: 2012-11-26
• Subjects: Older people -- Dental care -- Periodicals; 617.60846
• DOI: 10.1111/ger.12015
• Languages: English
• ISSNs: 0734-0664

Abstract

<abstract abstract-type="main" id="ger12015-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ger12015-sec-0001" sec-type="section"> <title>Objectives</title> <p>This longitudinal study evaluated the relationship between low renal function and tooth loss in elderly subjects.</p> </sec> <sec id="ger12015-sec-0002" sec-type="section"> <title>Material and methods</title> <p>Subjects comprised 406 female subjects (55–74 years old) who agreed to participate in a baseline examination and a follow‐up examination after 5 years. Serum cystatin C levels were used to assess renal function. Multiple logistic regression analysis was used to evaluate the relationship between tooth loss and change in serum cystatin C levels over 5 years. Tooth loss over 5 years (0: no, 1: yes) was used as the dependent variable. Seven variables were used as independent variables, including change in serum cystatin C levels over 5 years.</p> </sec> <sec id="ger12015-sec-0003" sec-type="section"> <title>Results</title> <p>Results of multiple logistic regression analysis showed that cystatin C change over 5 years, age, number of remaining teeth at baseline, number of sites with ≥4 mm clinical attachment level at baseline and serum 25‐hydroxyvitamin D levels at baseline were significantly associated with tooth loss. The odds ratio for tooth loss with cystatin C change over 5 years was 7.70 (<italic>p </italic>=<italic> </italic>0.029).</p> </sec> <sec id="ger12015-sec-0004" sec-type="section"> <title>Conclusion</title> <p>This study indicates a relationship between serum cystatin C levels and number of missing teeth, and thus suggests that low renal function is associated with tooth loss.</p> </sec> </abstract>