Extra-CNS metastasis from glioblastoma: a rare clinical entity. Issue 5 (May 2015)

• Record Type: Journal Article
• Authors: Awan, Musaddiq; Liu, Stanley; Sahgal, Arjun; Das, Sunit; Chao, Samuel T; Chang, Eric L; Knisely, Jonathan PS; Redmond, Kristin; Sohn, Jason W; Machtay, Mitchell; Sloan, Andrew E; Mansur, David B; Rogers, Lisa R; Lo, Simon S
• Is Part Of: Expert review of anticancer therapy. Volume 15:Issue 5(2015)
• Page Start: 545
• Page End: 552
• Publication Date: 2015-05
• Subjects: Cancer -- Treatment -- Periodicals; 616.99406
• DOI: 10.1586/14737140.2015.1028374
• Languages: English
• ISSNs: 1473-7140

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Extra-CNS metastasis from glioblastoma (ECMGBM) is an emerging but little known clinical entity. We review pre-clinical and translational publications assessing the ability of GBM to spread locally and outside the CNS. Reported cases demonstrating ECMGBM are reviewed providing a summary of presentations for the entity. Special attention is placed on transmission of GBM through organ transplantation. Finally, predictions are made as to the future significance of ECMGBM, especially in the context of better outcomes in CNS GBM.</p> </abstract>