Morbidity and mortality in hospitalised neonates in central Vietnam. (9th March 2015)

• Record Type: Journal Article
• Authors: Tran, Hoang T.; Doyle, Lex W.; Lee, Katherine J.; Dang, Na M.; Graham, Stephen M.
• Is Part Of: Acta pædiatrica. Volume 104:Number 5(2015:May)
• Page Start: e200
• Page End: e205
• Publication Date: 2015-03-09
• Subjects: Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.12960
• Languages: English
• ISSNs: 0803-5253

Abstract

<abstract abstract-type="main" id="apa12960-abs-0001"> <title>Abstract</title> <sec id="apa12960-sec-0001" sec-type="section"> <title>Aim</title> <p>This study explored neonatal morbidity and mortality in hospitalised patients in central Vietnam and risk factors associated with mortality.</p> </sec> <sec id="apa12960-sec-0002" sec-type="section"> <title>Methods</title> <p>We conducted a prospective cohort study of all newborn infants (<28 days) hospitalised in a neonatal unit over a 1‐year period and followed until discharge. The main outcome measures were case fatality rate and the rate of different clinical diagnoses.</p> </sec> <sec id="apa12960-sec-0003" sec-type="section"> <title>Results</title> <p>There were 2555 admissions during the study period. The leading primary causes of admissions were infections (41%), haematological problems such as jaundice (23%) and prematurity and its complications (18%). The overall case fatality rate was 8.6%, and it was 59% among very low‐birthweight (<1500 g) neonates. Mortality was inversely associated with birthweight and gestational age. Of the 220 deaths, 57% occurred within the first 7 days of life. Although the causes of death were often multifactorial, the leading primary causes were infections (32%), prematurity and its complications (25%), birth defects (24%) and birth asphyxia (6%). Risk factors associated with death were being outborn, early gestational age, small for gestational age, confirmed sepsis and birth defects.</p> </sec> <sec id="apa12960-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Mortality rates were high among hospitalised neonates in central Vietnam, and this paper suggests interventions that might improve outcomes<bold>.</bold></p> </sec> </abstract>