Acute cardiac sympathetic disruption and left ventricular wall motion abnormality in takotsubo syndrome. (March 2015)

• Record Type: Journal Article
• Authors: Y-Hassan, Shams
• Is Part Of: Acute cardiac care. Volume 17:Number 1(2015)
• Page Start: 24
• Page End: 25
• Publication Date: 2015-03
• Subjects: Cardiac intensive care -- Periodicals; Cardiovascular system -- Diseases -- Treatment -- Periodicals; 616.12028
• DOI: 10.3109/17482941.2014.989858
• Languages: English
• ISSNs: 1748-2941

Abstract

<abstract> <title>Abstract</title> <p>Takotsubo syndrome (TS) is characterized by a unique pattern of transient circumferential left ventricular wall motion abnormality (LVWMA). The LVWMA in TS may be localized to the apical, mid-apical, mid-ventricular, mid-basal or basal regions of the left ventricle. Focal and generialized (global) LVWMA have also been reported. In the acute phase of TS, the hyperkinetic valve-like motion of the basal segments and/or the hyperkinetic slingshot-like motion of the apical segments combined with the firm stunned a-, hypokinetic segments result in a conspicuous left ventricular ballooning during systole. The LVWMA in TS follows most probably the local cardiac sympathetic nerve distribution and caused by local cardiac sympathetic disruption and noradrenaline spillover.</p> </abstract>