Application value of MRI combined with positron emission tomography (PET)/CT in diagnosis and preoperative staging of tongue squamous cell carcinoma. Issue 2 (5th March 2015)

• Record Type: Journal Article
• Authors: Chen, Wenbo; Zhang, Chunxing; Zhang, Shuixing; Liang, Long; Zhang, Bin; Liu, Chunling; Zhang, Zhonglin; Liang, Changhong
• Is Part Of: Journal of medical imaging and radiation oncology. Volume 59:Issue 2(2015:Apr.)
• Page Start: 170
• Page End: 178
• Publication Date: 2015-03-05
• Subjects: Radiology, Medical -- Periodicals; Radiology, Medical -- Australasia -- Periodicals; 616.0757
• DOI: 10.1111/1754-9485.12282
• Languages: English
• ISSNs: 1754-9477

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jmiro12282-sec-0001" sec-type="section"> <title>Introduction</title> <p>This study aimed to compare and analyse the findings of tongue squamous cell carcinoma (TSCC) on MRI and positron emission tomography (PET)/CT and explore the diagnostic utility of combined MRI‐PET/CT in the diagnosis and preoperative staging of TSCC.</p> </sec> <sec id="jmiro12282-sec-0002" sec-type="section"> <title>Methods</title> <p>A prospective analysis of MRI and PET/CT data in 18 TSCC cases was performed. Cases were comprehensively staged on MRI and PET/CT preoperatively according to American Joint Committee on Cancer (AJCC) staging criteria and confirmed by pathological results.</p> </sec> <sec id="jmiro12282-sec-0003" sec-type="section"> <title>Results</title> <p>The highest and lowest sensitivities of preoperative AJCC staging I–IV using MRI alone, PET/CT alone and combined MRI‐PET/CT were 100.0%, 100.0% and 100.0% (stage II) and 50.4%, 55.6% and 55.6% (stage I), respectively. The highest specificities were 100.0%, 100.0% and 100.0% (stage II), and the highest correct rates were 100.0%, 96.5% and 100.0% (stage II). Compared with the postoperative pathological staging, preoperative staging showed no significant difference for stages I–II and IV (<italic>P</italic> > 0.05); however, stage III showed a significant difference (<italic>P</italic> < 0.05). When combined MRI‐PET/CT was compared with MRI alone in the accuracy of preoperative TSCC staging, there was no significant difference for stages I–III (<italic>P</italic> > 0.05), but there was a significant difference for stage IV (<italic>P</italic> < 0.05).</p> </sec> <sec id="jmiro12282-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Combined MRI and PET/CT could serve as an important tool for the accurate diagnosis and preoperative staging of TSCC and could improve the accuracy of preoperative TSCC staging.</p> </sec> </abstract>