Towards validating new enzymatic routes for synthetic conversion: 7, 10‐bis‐O‐(2, 2, 2‐trichloroethoxycarbonyl)‐10‐deacetyl baccatin III–ethyl acetate–water (1/1/1). Issue 3 (13th February 2015)

• Record Type: Journal Article
• Authors: Wang, Li; Li, Ya‐jun; Li, Zheng‐wei
• Is Part Of: Acta crystallographica. Volume 71:Issue 3(2015:Mar.)
• Page Start: 191
• Page End: 194
• Publication Date: 2015-02-13
• Subjects: Crystallography -- Periodicals; Crystals -- Periodicals; 548.3
• DOI: 10.1107/S2053229614027399
• Languages: English
• ISSNs: 2053-2296

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The title compound, C₃₄H₃₈Cl₆O₁₄·C₄H₈O₂·H₂O, prepared by the reaction of 10‐deacetyl baccatin III with 2, 2, 2‐trichloroethyl chloroformate in pyridine, crystallizes <italic>via</italic> strong intermolecular hydrogen bonds and noncovalent interactions between 7, 10‐bis‐<italic>O</italic>‐(2, 2, 2‐trichloroethoxycarbonyl)‐10‐deacetyl baccatin III (7, 10‐di‐Troc‐DAB), water and ethyl acetate. A detailed comparison of the molecular conformation with those of related structures is presented.</p> </abstract>