CBr4‐Mediated Cross‐Dehydrogenative Coupling Reaction of Amines. Issue 15 (23rd February 2015)

• Record Type: Journal Article
• Authors: Huo, Congde; Xie, Haisheng; Wu, Mingxia; Jia, Xiaodong; Wang, Xicun; Chen, Fengjuan; Tang, Jing
• Is Part Of: Chemistry. Volume 21:Issue 15(2015)
• Page Start: 5723
• Page End: 5726
• Publication Date: 2015-02-23
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201500453
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A novel CBr₄‐mediated dehydrogenative Povarov/aromatization tandem reaction of glycine derivatives with alkenes, leading to complex quinoline derivatives, and a CBr₄‐mediated dehydrogenative CH functionalization of <italic>N</italic>‐aryl tetrahydroisoquinolines with nucleophiles to form CC and CP bonds are reported. The reactions were performed under very simple and mild reaction conditions; only CBr₄ was used as a promoter. A plausible mechanism involving a radical process is proposed.</p> </abstract>