Hybrid Materials: Theranostic USPIO‐Loaded Microbubbles for Mediating and Monitoring Blood‐Brain Barrier Permeation (Adv. Funct. Mater. 1/2015). (January 2015)

• Record Type: Journal Article
• Authors: Lammers, Twan; Koczera, Patrick; Fokong, Stanley; Gremse, Felix; Ehling, Josef; Vogt, Michael; Pich, Andrij; Storm, Gert; van Zandvoort, Marc; Kiessling, Fabian
• Is Part Of: Advanced functional materials. Volume 25:Number 1(2014)
• Page Start: 2
• Page End: 2
• Publication Date: 2015-01
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201570002
• Languages: English
• ISSNs: 1616-301X

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adfm201570002-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Enabling safe and efficient drug delivery across the blood‐brain barrier (BBB) remains to be challenging. On page 36 of this issue, T. Lammers, P. Koczera, F. Kiessling, and colleagues show that polymer‐based microbubbles, containing iron oxide nanoparticles within their shell, can be employed to mediate and monitor BBB permeation. Such theranostic constructs and concepts are considered to be useful for tailoring the treatment of central nervous system disorders. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh30v8wztj" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>