Impact of recipient morbid obesity on outcomes after liver transplantation. (February 2015)

• Record Type: Journal Article
• Authors: Singhal, Ashish; Wilson, Gregory C.; Wima, Koffi; Quillin, R. Cutler; Cuffy, Madison; Anwar, Nadeem; Kaiser, Tiffany E.; Paterno, Flavio; Diwan, Tayyab S.; Woodle, E. Steve; Abbott, Daniel E.; Shah, Shimul A.
• Is Part Of: Transplant international. Volume 28:Number 2(2015:Feb.)
• Page Start: 148
• Page End: 155
• Publication Date: 2015-02
• Subjects: Transplantation of organs, tissues, etc -- Periodicals; 617.95405
• DOI: 10.1111/tri.12483
• Languages: English
• ISSNs: 0934-0874

Abstract

<abstract abstract-type="main" id="tri12483-abs-0001"> <title>Summary</title> <p>The aim of this study was to analyze the impact of morbid obesity in recipients on peritransplant resource utilization and survival outcomes. Using a linkage between the University HealthSystem Consortium and Scientific Registry of Transplant Recipients databases, we identified 12 445 patients who underwent liver transplantation (LT) between 2007 and 2011 and divided them into two cohorts based on recipient body mass index (BMI; &lt;40 vs. ≥40 kg/m²). Recipients with BMI ≥40 comprised 3.3% (<italic>n</italic> = 416) of all LTs in the studied population. There were no significant differences in donor characteristics between two groups. Recipients with BMI ≥40 were significant for being female, diabetic, and with NASH cirrhosis. Patients with a BMI ≥40 had a higher median MELD score, limited physical capacity, and were more likely to be hospitalized at LT. BMI ≥40 recipients had higher post‐LT length of stay and were less often discharged to home. With a median follow‐up of 2 years, patient and graft survival were equivalent between the two groups. In conclusion, morbidly obese LT recipients appear sicker at time of LT with an increase in resource utilization but have similar short‐term outcomes.</p> </abstract>